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Heppner et al., 2015b)

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Heart and kidney protection While clinical trials have yet to study the long-term benefits of Soliqua and Xultophy, research suggests that GLP-1s on their own can help protect the heart and kidneys

Human dipeptidyl peptidase IV gene promoter: tissue-specific regulation from a TATA-less GC-rich sequence characteristic of a housekeeping gene promoter

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Hypoglycaemia risk increases when GLP-1 agonists are combined with insulin or sulphonylureas, requiring careful medication review and dose adjustment