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Description
The pressure at your lower esophageal sphincter naturally decreases when you are in a supine, or horizontal position

Consistently under-eating can increase the risk of nutrient deficiencies, fatigue, and lean muscle loss

Nausea is the most common, affecting roughly 40% of patients in clinical trials
It is not so much another source of bias as a clue that other biases may be at work

Gastroenterol., 2007
16% identified as Hispanic or Latino ethnicity
