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Notably, considerable metabolic improvement was achieved at relatively low doses of GLP1/E, thus increasing the safety margin of this compound, which did not cause uterotrophic effects per se

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22 Several other studies showed that there was no significant relationship between GLP-1 RAs and DR worsening, including one study by Joo et al in which manual review of the data was conducted to ensure accuracy in the ICD coding used to determine outcomes