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IL-6 has shown also to induce the secretion of intestinal GLP-1, indirectly via the release of adipocytes derived Leptin (227)

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Reported harms include severe and persistent gastrointestinal issues (e.g., obstructive ileus, alleged gastroparesis/slow gastric emptying), bowel obstruction, and vision problems consistent with NAION

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S.AnzaiA.et al (2019)