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Moreover, probiotics primarily modulate gut microbiota, which produce an array of metabolites

Aronne and published in the New England Journal of Medicine

Storgaard, H., Cold, F., Gluud, L

Metformin-Induced Glucagon-Like Peptide-1 Secretion Contributes to the Actions of Metformin in Type 2 Diabetes

Basu A, Charkoudian N, Schrage W, Rizza RA, Basu R, Joyner MJ

Reducing Appetite The influence of GLP-1 on brain regions is rather direct
