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In 14 patients with coronary artery disease and good LV function, intravenous GLP-1 infusion improved global and regional wall LV function on dobutamine stress echocardiography compared with control [92]

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Preclinical studies in diet-induced obesity rodent models are ongoing to evaluate its efficacy, safety, and tolerability as a potential therapy for type 2 diabetes and obesity

These regions are part of the limbic-hypothalamic circuit (141)