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Effect of semaglutide on major adverse cardiovascular events by baseline kidney parameters in participants with type 2 diabetes and at high risk of cardiovascular disease: SUSTAIN 6 and PIONEER 6 post hoc pooled analysis
Post-marketing data have also noted rare risks such as gallbladder disease, acute kidney injury in volume-depleted patients, and potential worsening of diabetic retinopathy during rapid glycaemic control [93]
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Estimates of clearance and volume of distribution ranged from 0.6 to 1.2 L/h [32, 33, 3642, 44] and from 11.0 to 24.7 L [32, 3642], respectively, and were consistent across populations: healthy/type 2 diabetes, race groups, age groups, injection sites and dose levels
A Quick Overview of GLP-1 Medicines GLP-1 medicines mimic the hormone glucagon-like peptide-1, released by your intestines
[DOI] [PubMed] [Google Scholar] 34.Morgan DE, Baron TH, Smith JK, Robbin ML, Kenney PJ
