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GLP-1 receptor agonists mimic a gut hormone that acts on appetite centers in the brain, which is how Cleveland Clinic describes the way GLP-1 agonists lower blood sugar and promote weight loss

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Higher protein intake is especially important since GLP-1 medications can significantly reduce appetite

[1] [2] This triple mechanism distinguishes it from earlier agents such as semaglutide (a GLP-1 agonist alone) and tirzepatide (a dual GIP/GLP-1 agonist)