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For instance, Gene Holcombe, who has been living with type 2 diabetes for 25 years, said he noticed improvements in his psoriatic arthritis after taking Mounjaro (tirzepatide, a dual GIP/GLP-1 receptor agonist)

In 731 patients with HFpEF and obesity, tirzepatide demonstrated a 38% reduction in the composite endpoint of cardiovascular death or worsening heart failure events (HR 0.62, 95% CI 0.410.95), representing one of the most significant treatment effects ever observed in HFpEF [90]

Notes to editor GLP-1 receptor agonists are used to treat type 2 diabetes and obesity, with active ingredients including exenatide, lixisenatide, liraglutide, dulaglutide or semaglutide

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Medication Tolerance : Some people develop a tolerance, leading to a Semaglutide weight loss slow down