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These steps align with Endocrine Society guidance to monitor efficacy, safety (especially hematocrit/erythrocytosis ), and prostate risk where appropriate

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This spike is driven by high utilization and complex PBM models, where opaque pricing and rebate structures can limit employers' ability to capture the lowest net drug prices

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Additional resistance mechanisms have also been elucidated

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doi: 10.1016/j.actpsy.2011.01.002

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