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327 In the inflammatory environment, the M1 to M2 shift promoted by GLP-1 is crucial for reducing the expression of inflammatory factors such as IL-6, TNF-, and iNOS

However, recent evidence from 7391 Roux-en-Y gastric bypass and 5872 sleeve gastrectomy individuals showed that at least one in six individuals experienced 10% weight gain or more after surgery [39]

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During times of rapid weight loss, the body can experience stress that causes it to deprioritize non-essential functions

Concurrently, evidence from studies with GF mice indicates a huge impact of the microbiota on EEC numbers (189)

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