metformin vs glp-1 for weight loss Loss: Does It Work? Results & Side Effects 7 Surprising Benefits of Metformin
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They are also not approved by the FDA or any other government agencies 3

Due to the limited research on microdosing, the body's long-term response to these reduced doses remains unpredictable

This matters because injections are a barrier for some patients
J Biol Chem (2013) 288:3558191

Prolonged treatment with liraglutide further improves cardiovascular outcome in patients with T2DM [621]

Supporting the body's own hormone response, through diet, lifestyle, and evidence-based supplementation, is a more sustainable approach than trying to replicate GLP-1 synthetically
