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Why Tackling Weight Matters Excess weight is associated with increased risks of severe health conditions such as type 2 diabetes, heart disease, sleep apnea, high blood pressure, joint pain, and certain types of cancer

Mean change in body weight from baseline to Week 52 was a secondary endpoint.* Comparable weight reduction with RYBELSUS 14 mg vs Jardiance PIONEER 2 study design 1,3 In an open-label trial with a primary endpoint of mean change in A1C from baseline to 26 weeks, 822 adult patients with type 2 diabetes on metformin were randomized to RYBELSUS 14 mg (n=411) or Jardiance 25 mg (n=410), both once daily

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Their enlargement often signals an immune response to infection, inflammation, or, less commonly, other conditions

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