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However, if the pen was unopened and should have been refrigerated, or if temperatures exceeded 30C, the medication may be compromised and should be discarded

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Wegovy slows gastric emptying, which may alter eating patterns

Meal sequence The order in which you eat in a meal can also influence the stimulation of GLP-1 and post-meal insulin and blood sugar responses

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This is not unique to Retatrutide and applies to any significant weight loss intervention, but it is worth factoring into a long-term safety plan