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These include necrotizing pancreatitis, a life-threatening inflammation of the pancreas

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Shi X, Jiang A, Qiu Z, Lin A, Liu Z, Zhu L, et al
These effects occurred more frequently at higher doses and were generally consistent with the known side effect profile of incretin-based therapies

The increased expression of tissue factor stimulated by LPS seems to be the result of TLR4 activation, since in TLR4 positive endothelial cells, the production of tissue factor was reduced by treatment with TLR4 antibody [65]
