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Lancet (2021) 398 Suppl 1:S15
When adverse effects mirror the peptides known physiological actions rather than off-target toxicity, the appropriate response may be signal bias or contextual restriction rather than target rejection
Sakamuri, S
GLP-1 receptors show up in areas of the brain tied to reward
Most patients notice appetite reduction within the first few weeks
Knockdown of TRIM8 alleviates dextran sulfate sodium-induced colitis in mice by inhibiting the NF-B signaling pathway
