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Do not use in patients with a previous serious hypersensitivity reaction to tirzepatide or any of the excipients in ZEPBOUND [see Contraindications (4) and Adverse Reactions (6.2)]

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Random sequence generation, allocation concealment, blinding of participants and personnel, and blinding of outcome assessors were clearly presented in six studies ( 3.4 Pancreatitis In our meta-analysis of nine RCTs, six trials reported pancreatitis events that occurred during the study period

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