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Adding to the concerns, there is a growing market for compounded versions of GLP-1 drugs and peptides sold online

When patients feel like theyre being guided not just sold to they stay loyal and refer others

Discuss treatment with a provider if you have bleeding disorders, take blood thinning medications, are immunosuppressed, prone to cold sores, or are pregnant, breastfeeding, or under 21 (use not recommended)

In a phase 2 study clinical trial evaluating its use in T2DM, orforglipron significantly decreased HbA1c to 2.1% compared to 1.1% for dulaglutide and 0.43% for placebo

But it also shifts the pharmacokinetics in ways the standard titration wasn't designed for
