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Due to their preclinical testing and lack of comparison with other dual receptor agonists such as tirzepatide, further studies are needed to determine whether the effects of these unimolecular compounds are superior to those of clinically tested drugs

These mechanisms are linked to slowed proliferation and enhanced apoptosis in preclinical studies

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doi: 10.1056/nejmoa2511774

Other typical reactions include: Stomach pain and digestive issues Headache and fatigue Dizziness and bloating Heartburn and acid reflux [2] Serious side effects are rare but can include pancreas inflammation, gallbladder problems, and kidney complications [2]