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Glucagon-like peptide-1 (GLP-1) receptor is widely distributed in the digestive system, cardiovascular system, adipose tissue and central nervous system

Results showed that in PA-treated HUVECs and HFD-fed ApoE/ mice, combination of metformin and liraglutide at lower dose significantly improved endothelial dysfunction compared with the single treatment

Glimepiride is a second-generation sulfonylurea that stimulates ...

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Esses avanos teraputicos marcam uma revoluo no manejo das doenas metablicas e da obesidade.Os tratamentos com agonistas dos receptores GLP-1 e GIP, embora eficazes no manejo da obesidade e dos distrbios metablicos, podem causar efeitos colaterais que frequentemente levam interrupo das terapias