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Semaglutide primarily works by activating the GLP-1 receptor, which helps regulate appetite, satiety, food noise, gastric emptying, and blood sugar-related signaling

Phase 1 - Starting and Ramping Up (month 1 to 3) Dose: If one has had no prior GLP-1 therapy, they will be started on a very low dose of 0.25mg a week

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After a movement and strength assessment, it became clear that while he had successfully lost weight, he had also lost meaningful lower-body strength

GLP-1 side effects, including GI symptoms and related dehydration, are often more pronounced during dose increases

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