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But health bosses warned that such compounds are illegal and could expose users to dangerous ingredients that can have serious health consequences

Similarly, if the finerenone trials would not have been done, one might draw the (erroneous) conclusion that MRAs do not work at all in CKD

Cardiovascular and Kidney Health with Semaglutide: In addition to its direct renal benefits, Semaglutide also has cardiovascular advantages, which indirectly support kidney health

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New England Journal of Medicine (2016) This cardiovascular outcomes trial enrolled 3,297 patients with type 2 diabetes and high cardiovascular risk, randomizing them to semaglutide or placebo for a median of 2.1 years

That said, absence of evidence is not evidence of safety