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Description
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Starting with a low dose and titrating gradually can help minimise these effects

Therefore, we sought to incorporate an acid substituent to improve both potency and physiochemical properties

May;166:S-591

Meanwhile, the emergence of orally active small-molecule GLP-1 receptor agonists like danuglipron and orforglipron, which are resistant to enzymatic degradation, marks a major advance in patient-friendly drug delivery
