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Neurogastroenterol Motil

Pharma companies like Roche, Amgen, Pfizer, and AstraZeneca are among the contenders expected to release additional obesity drugs in the next three to four years

A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism
Maintaining adequate hydration is important, as dehydration from gastrointestinal side effects can lead to acute kidney injury in severe cases
GIP may also help regulate food intake and glucose metabolism when given in combination with a GLP-1 receptor agonist (de Mesquita et al., 2023)
