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[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Badve SV, Bilal A, Lee MMY, Sattar N, Gerstein HC, Ruff CT, et al

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Beyond weight outcomes, the Phase 2 obesity trial also reported improvements in several cardiometabolic markers, including: Reductions in waist circumference Improvements in fasting glucose and insulin sensitivity Favourable changes in blood pressure and lipid profiles Phase 3 trials understood to form part of the TRIUMPH programme are now underway, evaluating retatrutide in broader populations including people with type 2 diabetes and cardiovascular disease