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Seek immediate medical attention (call 999 or attend A&E) if you develop: Severe, unrelenting abdominal pain Signs of severe dehydration with confusion or altered consciousness Persistent vomiting with inability to retain any fluids for more than 24 hours Chest pain or difficulty breathing alongside gastrointestinal symptoms For patients with diabetes taking GLP-1 medications, persistent vomiting poses additional risks

[7] The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a Drug Safety Update recommending periodic B12 monitoring in patients on long-term metformin therapy

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Solutions to improve your metabolic health

Outcome 1: Drinking The first outcome was to simply ask people to record how much they drank in daily life
