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If your profile shows reduced GLP-1 receptor sensitivity, microdosing may help you avoid hitting a plateau, whereas high-responder genetics might benefit from microdosing's gentler entry point

Wegovy is a glucagon-like peptide-1 (GLP-1) receptor agonist, and the new dose is approved for patients with obesity of at least 1 weight-related medical condition

Given the observed increased risk of colorectal cancer among patients receiving GLP-1 receptor agonists, clinicians should approach long-term prescribing of these agents with careful consideration, particularly in individuals with additional risk factors for colorectal cancer, such as a family history, obesity, inflammatory bowel disease, or long-standing type 2 diabetes

Liraglutide (Victoza, Saxenda) Blood sugar changes Headache Heartburn Constipation Vomiting Stomach pain Increased feelings of depression Mood changes Phentermine-Topiramate (Qsymia) Changes in taste Tingling, itching, burning, or prickling in your extremities Dry mouth Trouble staying focused Irritability Dizziness Constipation Numbness Headache Naltrexone-Bupropion (Contrave) Orlistat (Xenical) Fatty stools Frequent bowel movements Gassiness Inability to hold in stool Setmelanotide (Imcivree) Are Weight Loss Medications Right for You