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[1] [5] According to the MHRA-approved Summary of Product Characteristics (SmPC), the most frequently reported adverse effects of Ozempic are gastrointestinal in nature

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Gut Microbes 14 , 2050635 (2022)

There is, however, a class of medications known as GLP-1 agonists, which a medical professional may consider in the treatment of diagnosable diseases such as Type 2 diabetes

Conclusion GLP-1 RAs held therapeutic potential for KOA patients with obesity or diabetes, but current evidence remained insufficient, warranting further high-quality RCTs and mechanistic studies to confirm their efficacy and safety

Carefully designed clinical studies are needed to assess the potential for treatment with selective cholinergic agonists or neurostimulating devices in such patients
