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Begin with a low dose

GLP-1RAs, with results indicating that oral semaglutide (14 mg) is likely to be cost-effective versus dulaglutide, exenatide (once weekly and twice daily), liraglutide, and lixisenatide in terms of achieving glycemic control targets [74]

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Graaf Cd, Donnelly D, Wootten D, et al

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Oral semaglutide is typically started at 3 mg once daily for 30 days, then increased to 7 mg daily, with an option to further increase to 14 mg daily based on individual treatment goals and tolerability.7 In individuals with T2DM, there seems to be a similar response between oral and subcutaneous semaglutide versions