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Participants (average HbA1c level of 8.3%89,90)) were randomized to receive albiglutide or a DPP-4 inhibitor (sitagliptin) based on presence of metformin therapy

At 48 weeks, relative liver fat reductions reached -81.7% and -86.0% with 8mg and 12mg doses respectively

doi: 10.3389/fmed.2025.1638981 Received 31 May 2025 Accepted 14 August 2025 Published 10 September 2025 Volume 12 - 2025 Edited by Iain Brownlee, Northumbria University, United Kingdom Reviewed by Qianqian Zhang, Anhui University of Chinese Medicine, China Ion Hobai, Massachusetts General Hospital and Harvard Medical School, United States Updates Copyright 2025 Ukwade, Hernandez, Modi, Raza, Siegel, Nwachukwu, Sarraf, Memon, Booth, Cooper, Boulay and Mutlu