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Fatigue is a recognised side effect when starting glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), or liraglutide (Victoza, Saxenda)

Sometimes, people with type 2 diabetes also need insulin

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When you exceed the amount your body is prepared to handle, the receptors for GLP-1 and GIP become overstimulated

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Several trial limitations, including the small sample size, limit the interpretation of these preliminary findings, which require validation in a larger trial