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Conversely, participants who were given a placebo (only diet and exercise) showed an average weight reduction between 0.2 and 3.0 kg

GLP-1 for weight loss Medically reviewed by Dr Crystal Wyllie Last reviewed: 19 Jun 2026 Glucagon-like peptide-1 (GLP-1) agonists are a popular weight loss treatment in the UK

Diabetologia (2010) 53(1):1539

For Ms Chambers, getting on Ozempic had little to do with vanity her doctor even told her that she was at risk of a heart attack if she did not lose weight
For comparison, the SURMOUNT-1 trial for tirzepatide showed an average of 20.9% weight loss at the highest dose over 72 weeks
So did his weight
