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Consequently, suppression of IL-1 via GLP-1 receptor mediation, particularly through the pathway involving PKC-mediated inhibition of the nucleotide-binding domain, leucine-rich-containing family, pyrin-domain-containing-3 (NLRP3) inflammasome, can further contribute to reducing the formation of a profibrotic environment

[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Najm A., Niculescu A.G., Grumezescu A.M., Beuran M