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GLP-1R KO mice have increased baseline left ventricular developed pressure (LVDP) during perfusion [201]
10.1124/jpet.114.220350 53 Heckman-StoddardB

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At 48 weeks, participants had lost an average of 24 percent of their body weight, or about 58 poundsmore than any other drug on the market

GLP-1 receptors in the brain The brain contains abundant GLP-1 receptors in key regions including the hippocampus, cerebral cortex, hypothalamus, thalamus, and globus pallidum 26

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