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S., Ortiz-Prado, E., Rico-Fontalvo, J., Gmez-Mesa, J.-E., Abreu-Lomba, A, & Rivera-Martnez, W.-A

Glucagon-Like Peptide-1 Receptor Agonist Dulaglutide Prevents Ox-LDL-Induced Adhesion of Monocytes to Human Endothelial Cells: An Implication in the Treatment of Atherosclerosis

Recent survey data highlight the ongoing divide in public and professional attitudes toward obesity

On a cellular level, the polarization of macrophages has been stimulated by this molecule, shifting them from the inflammatory M1 phenotype to the anti-inflammatory M2 phenotype, which plays a vital role in tissue regeneration as well in reducing inflammation, as they produce cytokines like IL-10 and TGF-[5]

Data availability Data for the trial are available upon reasonable request to the corresponding author

We nevertheless observed, by RICCS analysis, a tendency for reduced co-diffusion of Laurdan with GLP-1R V229A under vehicle conditions, an effect normally only present in stimulated conditions for WT receptor, with no further change after agonist stimulation observed for the V229A mutant, suggesting a different pattern of interaction of V229A versus WT GLP-1R with plasma membrane lipids