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Patients are encouraged to track changes in body weight, measurements, appetite, and energy, as well as non-scale changes such as better sleep or improved mood, and the care team uses this information to refine the plan so it remains both safe and effective over time

10.1111/aji.12470 [DOI] [PubMed] [Google Scholar] Luo X., Ding L., Xu J., Williams R

People on the 2.4 mg dose lost more weight than those on other doses: Two trials (STEP 1 and STEP 3) found an average weight loss of 12% and 13% on the 2.4 mg dose in just over a year (68 weeks)

Preclinical studies in diet-induced obesity rodent models are ongoing to evaluate its efficacy, safety, and tolerability as a potential therapy for type 2 diabetes and obesity

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If you have documented Cushings syndrome in remission with persistent metabolic syndrome, your endocrinologist can submit a prior authorization citing medical necessity elevated insulin resistance, central obesity, and failed dietary intervention strengthen the case