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Description
26.Administration F and D

Aggravating the above mentioned challenges, the classic treatments for T2DM (sulfonylurea [SU] and insulin) are associated with clinically relevant weight increases

GLP-1 has opposing effects on hepatic lipid accumulation and plasma lipid levels, which has recently broadened its clinical use in pharmacological therapy of metabolic syndrome and steatohepatitis 8,9

Most GLP-1s are synthesized via Solid-Phase Peptide Synthesis (SPPS), where amino acids are added one-by-one to a resin base

10.1007/s12035-025-05113-y 7 AndersonF
McClean PL, Parthsarathy V, Faivre E, Hlscher C
