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faecalis supernatants were capable of disrupting the colonic epithelial monolayer and cleaving GLP-1 in a gelE-dependent manner (Levalley et al., 2020)

GLP-1, or glucagon-like peptide-1, is a naturally occurring hormone in the body that plays a crucial role in regulating blood sugar, appetite, and digestion

The effects of GLP-1RAs on thyroid cancer risk Multiple retrospective observational studies and spontaneous case reports suggest a possible association between GLP-1RAs and an elevated risk of thyroid cancer [20, 21]

Through its interaction with the GLP-1 receptor (GLP-1R), GLP-1 participates in the regulation of glucose homeostasis

Mechanisms of NMDA receptor- and voltage-gated l-type calcium channel-dependent hippocampal LTP critically rely on proteolysis that is mediated by distinct metalloproteinases

This discovery was a watershed moment: nature had already evolved a stable GLP-1 analog