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The present systematic review and meta-analysis were undertaken to comprehensively assess the impact of GLP-1 RAs on testosterone levels in men, synthesizing the latest clinical data to better understand their metabolic and endocrine roles
The search terms used for the diabetes population included "Diabetes Mellitus, Type 2", "Diabetic Nephropathies" and synonyms such as T2D, T2DM, NIDDM and adult-onset diabetes
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Clinical trial number Not applicable
Practical Strategies to Reduce Diarrhea While on GLP-1 Dietary modifications are the first line of defense against GLP-1-related diarrhea
GLP-1RAs also upregulate sirtuin-1 (SIRT1) indirectly (53), which deacetylates autophagy-related proteins and promotes autophagosome formation
