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In addition, evidence suggests that GLP-1 RAs may increase pancreatic enzyme secretion, while the expression and subsequent stimulation of GLP-1 receptors in pancreatic islet and exocrine duct cells have been correlated with overgrowth of the ductal epithelial cells, resulting in hyperplasia and chronic low-grade or acute inflammation, potentially leading to pancreatitis [89]

Less common but serious: pancreatitis, gallbladder problems, kidney injury (often from dehydration), hypoglycemia (especially with insulin/sulfonylureas), and rare allergic reactions

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The least squares mean was estimated using an MMRM in all randomized participants who had available data (placebo, n = 33

Obesity causes persistent fatigue through sleep apnea, chronic inflammation, insulin resistance, reduced cardiovascular capacity, and joint pain that limits activity

While this provider meets basic standards, there are some areas for improvement