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Other potential causes include: Certain medications, including GLP-1 receptor agonists, opioid pain medications, and some antidepressants Previous stomach or abdominal surgery that affects nerves involved in digestion Neurological conditions such as Parkinson's disease or multiple sclerosis Viral infections that temporarily disrupt nerve function Autoimmune disorders that damage nerves or muscles involved in digestion Connective tissue diseases such as scleroderma In some cases, doctors can't identify a specific cause

Nevertheless, patients using insulin or sulfonylureas may require dose adjustments when initiating potent incretin-based therapy because improved glycemia and reduced caloric intake can increase hypoglycemia risk when combined with therapies that independently lower glucose

Individuals with a history of pancreatitis should use tirzepatide with caution or consider alternative therapies

Association of glucagon-like peptide-1 receptor agonist with progression to liver cirrhosis and alcohol-related admissions in patients with alcohol use disorder and diabetes: a retrospective cohort study

Through Hims & Hers, weight loss medications start at $79 per month for oral medication kits and $199 per month for compounded GLP-1 injections, according to the company