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Indias drug regulator steps up action against unauthorised sale and promotion of GLP-1 weight-loss drugs, warning of health risks and tightening inspections across pharmacies and online platforms.

Unlike injectable semaglutide or tirzepatide, this is a once-daily pilland if it progresses successfully through development, it could change patient access.

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Conversely, RNA interference (i)-induced knockdown of SIRT1 attenuated the lipolytic and oxidative responses to exendin-4 in differentiated 3T3-L1 adipocytes

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