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ELIXA trial included patients with recent cardiovascular event (patients with acute coronary syndrome 180 days before randomization), and although there was no benefit in MACE reduction in lixisenatide treated patients compared to placebo, results revealed cardiovascular safety of lixisenatide in this specific high risk population (38, 40)

Potential risks include, but are not limited to: pancreatitis (inflammation of the pancreas), gallbladder problems, kidney issues, thyroid problems, and retinal (eye) problems

Any retatrutide obtained outside of a formal, ethics-approved clinical trial is classified as a research chemical and is not intended for human use under current UK regulations

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Several evidence-based strategies can help minimise nausea and improve tolerability whilst taking Ozempic

This delayed gastric emptying may lead to increased acid buildup or allow stomach acid more opportunity to irritate the esophagus, making reflux or heartburn more likely