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Of weight lost with semaglutide, approximately 45% is from lean mass, while with tirzepatide, it is 25%

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Improvement in lipid profile (reduction in triglycerides and LDL cholesterol)

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Evidence-based comparison of ecnoglutide (cAMP-biased GLP-1 agonist) and semaglutide (selective GLP-1 agonist), including SLIMMER Phase 3, STEP, and SELECT trial data.