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The most frequently reported side effects with tirzepatide dosing for weight loss in units include nausea, diarrhea, decreased appetite, vomiting, constipation, and abdominal discomfort

These typically occur during dose increases and improve over time

The study showed significant decreases in HOMA2-B scores, proinsulin/insulin ratios, and proinsulin/C-peptide ratios in both tirzepatide (all doses) and dulaglutide compared to placebo [66]

Its a prescription medication that targets two key hormones GLP-1 and GIP which help regulate hunger, energy, and metabolism

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Timing also matters