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GLP-1 RAs have been found to improve overall cardiovascular health and reduce major adverse cardiovascular events (MACE) by improving the endothelial function of the vasculature and lowering ANP (atrial natriuretic peptide) production, leading to reduced blood pressure

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Research has demonstrated that multiple immune cells are involved in the etiology and evolution of RA, including macrophages, monocytes, neutrophils, and T cells [231]