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Discontinuation Rates The 11.2% discontinuation rate due to adverse events at the 12mg dose provides context for real-world expectations

Not everyone who takes semaglutide will experience side effects

The first click indicates the injection has started and the second click confirms the dose has been delivered

Serious Adverse Events Serious adverse events are uncommon but have been documented and warrant appropriate monitoring: Pancreatitis : Cases of acute pancreatitis have been reported (approximately 0.2-0.3% incidence)

PKA stimulates the synthesis of transcription factors including cAMP response element-binding protein (CREB) in the nucleus, a promoter of gene expression