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Whilst the heart rate increases observed were statistically significant, they were not associated with a higher rate of serious adverse cardiac events in the Phase 2 data

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Other Causes of Joint Pain Aside from weight, other factors that may cause osteoarthritis or joint pain may include: 6 Age Past injury or surgery on a joint Sports with a lot of jumping, running, or twisting that overuse the joint A family history of osteoarthritis

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