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It compared oral semaglutide at a target dose of 14 mg once daily (with dose escalation from 3 mg to 7 mg) versus matching placebo, both added to standard of care for diabetes and cardiovascular risk management

Synaptic Dopamine Reuptake and Degradation Dopamine is released from the presynaptic terminal, diffuses over the synaptic cleft and activates Dopaminergic receptors (D1-D5 receptors)