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Regarding weight loss, the SURMOUNT-1 trial revealed meaningful results, with participants achieving body weight reductions of up to 20.9% when treated with 15 mg doses over 72 weeks [46]
The medicine doesnt replace lifestyle changes, says Pepin
Aulinger BA, Bedorf A, Kutscherauer G et al (2014) Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade
The trade-off involves accepting higher variability and reduced regulatory oversight in exchange for accessibility
Your provider monitors how you respond, adjusts timing, and watches for problems you might not notice yourself
Kushner, New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics, Annual Review of Medicine 2023
